How functional neuroimaging is informing cognitive neurobiological models of auditory verbal hallucinations

Introduction Auditory verbal hallucinations (AVHs), or “hearing voices”, are a complex phenomenon characterised by abnormal perceptions of speech occurring in the absence of an appropriate external stimulus.1 Hallucinations of this modality hold great diagnostic significance, with Schneider’s (1959) first-rank symptoms of schizophrenia (including AVHs) still recognised today by major classification systems such as the International […]

Not just a four-letter word: The role of neuroendocrine factors in romantic love

The dopamine reward pathway

Introduction In his poem ‘Love’s Trinity’, Victorian poet laureate Alfred Austin presents a holistic view of love, describing its impact on both our psyche and physiology:1,2 ‘Soul, heart, and body, we thus singly name, Are not in love divisible and distinct, But each with each inseparably link’d’ (A Austin).3 Romantic love has influenced literature and […]

SYMPOSIUM 2: The psychopharmacology of emerging calcium channel targets

Calcium ions (Ca2+) are universal intracellular messengers and, through selectively permeable calcium channels, can mediate and drive many important physiological processes. However, excessive calcium channel activation can lead to excitotoxicity within cells. Thus, it is imperative that the opening of these channels is well and precisely regulated. Altered calcium function has become of recent interest […]